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Technical Data
| Formula | C14H22N2O |
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| Molecular Weight | 234.34 | CAS No. | 137-58-6 | |
| Solubility (25°C)* | In vitro | DMSO | 47 mg/mL (200.56 mM) | |
| Ethanol | 47 mg/mL (200.56 mM) | |||
| Water | 9 mg/mL (38.4 mM) | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Lidocaine (Alphacaine) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. | ||
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Protocol (from reference)
Selleck's Lidocaine has been cited by 6 publications
| Moderate heart rate reduction promotes cardiac regeneration through stimulation of the metabolic pattern switch [ Cell Rep, 2022, 38(10):110468] | PubMed: 35263588 |
| Lidocaine suppresses the malignant behavior of gastric cancer cells via the c-Met/c-Src pathway [ Exp Ther Med, 2021, 21(5):424] | PubMed: 33747163 |
| High-resolution optoacoustic imaging of tissue responses to vascular-targeted therapies. [ Nat Biomed Eng, 2020, 4(3):286-297] | PubMed: 32165736 |
| Lidocine potentiates the cytotoxicity of 5-fluorouracil to choriocarcinoma cells by downregulating ABC transport proteins expression. [ J Cell Biochem, 2019, 120(10):16533-16542] | PubMed: 31081972 |
| Histamine Receptor Antagonists, Loratadine and Azelastine, Sensitize P-gp-overexpressing Antimitotic Drug-resistant KBV20C Cells Through Different Molecular Mechanisms. [ Anticancer Res, 2019, 39(7):3767-3775] | PubMed: 31262903 |
| Cyclopiazonic acid, an inhibitor of calcium-dependent ATPases with antiviral activity against human respiratory syncytial virus [Cui R, et al. Antiviral Res, 2016, 132:38-45] | PubMed: 27210812 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.