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Technical Data
| Formula | C9H10O3 |
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| Molecular Weight | 166.17 | CAS No. | 552-41-0 | |
| Solubility (25°C)* | In vitro | DMSO | 33 mg/mL (198.59 mM) | |
| Ethanol | 33 mg/mL (198.59 mM) | |||
| Water | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Preparing Stock Solutions
Biological Activity
| Description | Paeonol (Peonol), a phenolic compound extracted from Chinese herbs Paeonia suffruticosa (moutan cortex) and Cynanchum paniculatum, inhibits MAO with an IC50 of about 50 μM. | ||||
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| Targets |
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| In vitro | Paeonol (Peonol) is a phenolic compound extracted from Chinese herbs Paeonia suffruticosa (moutan cortex) and Cynanchum paniculatum. It has demonstrated significant MAOI activity. MAO-A and MAO-B inhibiting effects with IC50 values of 54.6 μM and 42.5 μM respectively. [1] Paeonol shows antimutagenic, anti-inflammatory and analgesic effects. [2] Paeonol also inhibits anaphylactic reaction by regulating histamine and TNF-α. [3] | ||||
| In vivo | LD50: Mice 608-899mg/kg (i.p.). [4] |
Protocol (from reference)
References
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Selleck's Paeonol has been cited by 2 publications
| Paeonol inhibits melanoma growth by targeting PD1 through upregulation of miR-139-5p [ Biochem Biophys Res Commun, 2023, 656:86-96] | PubMed: 36958259 |
| Xanthohumol inhibits colorectal cancer cells via downregulation of Hexokinases II-mediated glycolysis. [ Int J Biol Sci, 2019, 15(11):2497-2508] | PubMed: 31595166 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.