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Technical Data
| Formula | C19H28NO3.Br |
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| Molecular Weight | 398.33 | CAS No. | 596-51-0 | |
| Solubility (25°C)* | In vitro | Water | 79 mg/mL (198.32 mM) | |
| DMSO | 65 mg/mL (163.18 mM) | |||
| Ethanol | 59 mg/mL (148.11 mM) | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Preparing Stock Solutions
Biological Activity
| Description | Glycopyrrolate (Glycopyrronium, Robinul, Gastrodyn) is a muscarinic antagonist used as an antispasmodic, in some disorders of the gastrointestinal tract, and to reduce salivation with some anesthetics. | |
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| In vitro | Glycopyrrolate inhibits EFS-induced contraction of guinea-pig trachea and human airways in a concentration-dependent manner. In competition studies, glycopyrrolate binds human peripheral lung and human airway smooth muscle (HASM) muscarinic receptors with affinities in the nanomolar range (Ki values 0.5–3.6 nM). Glycopyrrolate showed no selectivity in its binding to the M1–M3 receptors. Kinetics studies show that glycopyrrolate dissociates slowly from HASM muscarinic receptors[1]. |
Protocol (from reference)
References
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Selleck's Glycopyrrolate has been cited by 1 publication
| Using Corneal Confocal Microscopy to Identify Therapeutic Agents for Diabetic Neuropathy [ J Clin Med, 2022, 11(9)2307] | PubMed: 35566433 |
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.