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Technical Data
| Formula | C75H70N6O6 |
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| Molecular Weight | 1151.39 | CAS No. | 3546-41-6 | |
| Solubility (25°C)* | In vitro | DMSO | 24 mg/mL (20.84 mM) | |
| Water | Insoluble | |||
| Ethanol | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Pyrvinium pamoate(Pyrvinium embonate) is an anthelmintic effective for pinworms. |
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Protocol (from reference)
Selleck's Pyrvinium pamoate has been cited by 11 publications
| Repurposing FDA-Approved Drugs for Temozolomide-Resistant IDH1 Mutant Glioma Using High-Throughput Miniaturized Screening on Droplet Microarray Chip [ Adv Healthc Mater, 2023, e2300591.] | PubMed: 37162029 |
| Synergistic effect of pyrvinium pamoate and posaconazole against Cryptococcus neoformans in vitro and in vivo [ Front Cell Infect Microbiol, 2022, 12:1074903] | PubMed: 36569209 |
| The FDA-Approved Drug Pyrvinium Selectively Targets ER+ Breast Cancer Cells with High INPP4B Expression [ Cancers (Basel), 2022, 15(1)135] | PubMed: 36612130 |
| The Casein kinase 1α agonist pyrvinium attenuates Wnt-mediated CK1α degradation via interaction with the E3 ubiquitin ligase component Cereblon [ J Biol Chem, 2022, 298(8):102227] | PubMed: 35780831 |
| β-catenin inhibitors ICG-001 and pyrvinium sensitize bortezomib-resistant multiple myeloma cells to bortezomib [ Oncol Lett, 2022, 24(1):205] | PubMed: 35720475 |
| Inhibiting Wnt/beta-catenin in CTNNB1-mutated endometrial cancer [ Mol Carcinog, 2021, 10.1002/mc.23308] | PubMed: 34038589 |
| Pyrvinium pamoate inhibits cell proliferation through ROS-mediated AKT-dependent signaling pathway in colorectal cancer [ Med Oncol, 2021, 38(2):21] | PubMed: 33554313 |
| In vitro and in vivo Study of Antifungal Effect of Pyrvinium Pamoate Alone and in Combination With Azoles Against Exophiala dermatitidis [ Front Cell Infect Microbiol, 2020, 10:576975] | PubMed: 33194816 |
| Synergistic Effect of Pyrvinium Pamoate and Azoles Against Aspergillus fumigatus in vitro and in vivo [ Front Microbiol, 2020, 11:579362] | PubMed: 33224118 |
| Reversal of Infected Host Gene Expression Identifies Repurposed Drug Candidates for COVID-19 [ bioRxiv, 2020, 2020/9/20.4.7.30734] | PubMed: 32511305 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.