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Technical Data
| Formula | C18H19N3O3S.HCl |
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| Molecular Weight | 393.89 | CAS No. | 302543-62-0 | |
| Solubility (25°C)* | In vitro | DMSO | 79 mg/mL (200.56 mM) | |
| Ethanol | 79 mg/mL (200.56 mM) | |||
| Water | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Rosiglitazone HCl is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells. | |
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Protocol (from reference)
Customer Product Validation
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Data from [J Leukoc Biol, 2014, 95(4), 587-98]
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Data from [J Leukoc Biol, 2014, 95(4), 587-98]
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Data from [Data independently produced by , , Reprod Toxicol, 2016, 61:162-8]
Selleck's Rosiglitazone HCl has been cited by 19 publications
| Generation of functionally competent hepatic stellate cells from human stem cells to model liver fibrosis in vitro [ Stem Cell Reports, 2022, 17(11):2531-2547] | PubMed: 36270282 |
| Elaiophylin reduces body weight and lowers glucose levels in obese mice by activating AMPK [ Cell Death Dis, 2021, 12(11):972] | PubMed: 34671010 |
| Oxygen-sensitivity and Pulmonary Selectivity of Vasodilators as Potential Drugs for Pulmonary Hypertension [ Antioxidants (Basel), 2021, 10(2)155] | PubMed: 33494520 |
| Recreating the Bone Marrow Microenvironment to Model Leukemic Stem Cell Quiescence [ Front Cell Dev Biol, 2021, 9:662868] | PubMed: 34589478 |
| Low-intensity pulsed ultrasound prevents angiotensin II-induced aortic smooth muscle cell phenotypic switch via hampering miR-17-5p and enhancing PPAR-γ [ Eur J Pharmacol, 2021, 911:174509] | PubMed: 34547245 |
| Traditional Chinese Medication Qiliqiangxin Attenuates Diabetic Cardiomyopathy via Activating PPARγ [ Front Cardiovasc Med, 2021, 8:698056] | PubMed: 34336956 |
| Inhibition of the activation of γδT17 cells through PPARγ-PTEN/Akt/GSK3β/NFAT pathway contributes to the anti-colitis effect of madecassic acid [ Cell Death Dis, 2020, 11(9):752] | PubMed: 32929062 |
| Peroxisome proliferator-activated receptor γ (PPARγ) suppresses the proliferation and metastasis of patients with urothelial carcinoma after renal transplantation by inhibiting LEF1/β-catenin signaling [ Bioengineered, 2020, 11(1):1350-1367] | PubMed: 33289586 |
| Inhibition of ACSL4 attenuates ferroptotic damage after pulmonary ischemia-reperfusion [ FASEB J, 2020, 10.1096/fj.202001758R] | PubMed: 33070393 |
| TRIM27-mediated ubiquitination of PPARγ promotes glutamate-induced cell apoptosis and inflammation [ Exp Cell Res, 2020, S0014-4827(20)30690-X] | PubMed: 33385414 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.