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Technical Data
| Formula | C7H5ClN2O |
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| Molecular Weight | 168.58 | CAS No. | 61-80-3 | |
| Solubility (25°C)* | In vitro | DMSO | 34 mg/mL (201.68 mM) | |
| Ethanol | 34 mg/mL (201.68 mM) | |||
| Water | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Zoxazolamine (NSC 24995, Contrazole) is a centrally acting myorelaxant, which is formerly used as an antispasmodic and uricosuric. |
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| In vitro | Zoxazolamine is in the centrally-acting muscle relaxant class of drugs, which reportedly act by decreasing CNS interneuronal activity. These drugs, but not anxiolytics, decrease dopaminergic turnover and induce a pacemaker-like discharge pattern in dopaminergic neurons.[1] Zoxazolamine is a member of the large class of biologically active 2-amino-2-oxazoles. Zoxazolamine is also used as a tool for assessing hepatic cytochrome P-450 activity.[2] |
Protocol (from reference)
References
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
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