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Abbreviations

Routes of drug administration
Route Abbreviation Description
Intracerebroventricular i.c.v. Into the ventricles of the brain
Intra-arterial i.a. Into the lumen of an artery
Intracerebral i.c. Into the brain
Intradermal i.d. Into the dermal layer of the skin
Intramuscular i.m. Into a skeletal muscle
Intragastric i.g. Into the stomach
Intraperitoneal i.p. Into the peritoneum (body cavity)
Intravenous i.v. Into a vein
Oral p.o. By mouth
Subcutaneous s.c. Under the skin
quaque die (Latin) q.d. once a day
bis in die (Latin) b.i.d. twice a day
ter in die (Latin) t.i.d. three times a day
Targets
Abbreviation Description
Abl V-abl Abelson murine leukemia viral oncogene homolog 1
ALK anaplastic lymphoma kinase
ATM Ataxia telangiectasia mutated
B-Raf B-Raf proto-oncogene serine/threonine-protein kinase (B-RAF), also known as V-raf murine sarcoma viral oncogene homolog B1
Bcl-2 B-cell lymphoma 2
Bcr breakpoint cluster region
Caspases cysteine-aspartic proteases or cysteine-dependent aspartate-directed proteases
CCR5 co-receptors chemokine receptor 5
CDK Cyclin-dependent kinase
CFTR potentiator Cystic fibrosis transmembrane conductance regulator
CTSK Cathepsin K
c-Kit CD117 (cluster of differentiation 117), also called KIT or C-kit receptor
c-Met mesenchymal-epithelial transition
DNA-PK DNA-dependent protein kinase
DPP-4 Dipeptidyl peptidase-4
EGFR Epidermal growth factor receptor
Factor Xa Stuart-Prower factor, an enzyme of the coagulation cascade
FGFR Fibroblast growth factor receptor
FLT-3 fms-like tyrosine kinase-3
FTS Farnesyl thiosalicylic acid
GSK-3 Glycogen synthase kinase 3
HER2 Human epidermal growth factor receptor 2
HDAC Histone deacetylase
HIF Hypoxia-inducible factor
HSP-70 heat-shock protein-70
HSP-90 heat-shock protein-90
IGF-1R Insulin-like growth factor 1 receptor
JAK Janus kinase
JNK c-Jun N-terminal kinases
Ksp Kinesin spindle protein
MAPK Mitogen-activated Protein Kinase
MEK MAPK/ERK kinase
mGluRs metabotropic glutamate receptors
mTOR Mammalian target of rapamycin
NF-kB Nuclear factor-κB
p38 MAPK p38 Mitogen-activated Protein Kinase
p53 protein 53 or tumor protein 53
PARP Poly (ADP-ribose) polymerase
PDGFR platelet-derived growth factor receptor
PDK-1 phosphoinositide-dependent kinase-1
Rho ρ factor
PI3K Phosphatidylinositol 3-kinases
PKC protein kinase C
PLK Polo-like kinase
Ras renin-angiotensin system
RNAP RNA Polymerase or RNApol
S1PR1 Sphingosine-1-phosphate receptor (S1P1) also known as endothelial differentiation gene 1 (EDG1)
sPLA2 Secreted phospholipase A2
Src Rous sarcoma oncogene cellular homolog
Stat Signal Transducers and Activator of Transcription
Survivin baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5
TGF Transforming growth factor
TNF Tumor necrosis factor
VEGFR Vascular Endothelial Growth Factor Receptor
Wnt a portmanteau of int and Wg and stands for "Wingless-related integration site"