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Mitochondria-Targeted Compound Library

Catalog No.L9900

A unique collection of 719 compounds targeting mitochondria, used for high-throughput screening (HTS) and high-content screening (HCS).

96 well plates

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Mitochondria-Targeted Compound Library Contents

Description & Advantages

•A unique collection of 719 mitochondria-targeted compounds for high throughput screening (HTS) and high content screening (HCS);
 
•A unique collection covers various aspects of mitochondrial function, such as Mitochondrial Metabolism, ATP Synthase, Mitophagy, Reactive Oxygen Species, mitochondria-associated hexokinase, Bcl-2, etc. It also includes other promising mitochondria-targeted compounds, such as lonidamine, paclitaxel, etc;
 
•Bioactivity and safety confirmed by preclinical research and /or clinical trials. Some inhibitors have been approved by FDA;
 
•Structurally diverse, medicinally active, and cell permeable;
 
•More detailed compound information with structure, IC50, and brief introduction;
 
•High purity and quality validated by NMR and HPLC;
 
• All compounds are in stock and continuously updated.

Product Details

Formulation 667 compounds pre-dissolved in 10mM DMSO, 41 compounds pre-dissolved in 10mM water, 11 compounds pre-dissolved in 2mM DMSO.
Container 96 Deep Well Plate Sealed With Aluminum Foil
Stability 12 months -20°C in DMSO
24 months -80°C in DMSO
Shipping Blue ice or dry ice

Case Studies using Selleck Compound Libraries

  • Application of GPCR Compound Library in liver cancer (This article was published in Nature (IF=43) and took about 15 months):

    Nature.2019;574(7777):268-272

  • Application of Kinase Inhibitor Library in colorectal cancer (This article was published in Nature Communications (IF=11) and took about 8 months):

    Nat Commun. 2019 16;10(1):2197

  • Application of FDA-approved Drug Library in antivirus (This article was published in Cell Research (IF=17) and took about 13 months):

    Cell Res. 2019;29(9):739-753

  • Application of FDA-approved Drug Library in metabolism (This article was published in Movement Disorders (IF=8) and took about 10 months):

    Mov Disord. 2019;34(3):323-334

  • Application of Epigenetics Compound Library in acute lymphoblastic leukemia (This article was published in Blood (IF=16) and took about 16 months):

    Blood. 2019 17;134(16):1323-1336

  • Application of Inhibitor Library in tumor immunology (This article was published in Cancer Immunol Res (IF=8.6) and took about 12 months):

    Cancer Immunol Res.2017;5(9):790-803

Mitochondria-Targeted Compound Library Composition

HTS Facility Partners