HomeDyes

Dyes

Catalog No. Product Name Information
S1917 Crystal Violet Crystal violet(Gentian Violet) is a triarylmethane dye.
S1924 Indocyanine green Indocyanine green(Cardiogreen) is a cyanine dye that binds to plasma proteins and lipoproteins. It is used in medical diagnostics. It is used for determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography. Indocyanine green-photodynamic therapy(ICG-PDT) induces apoptosis in HGF cells at transcriptome level.
S2384 Hematoxylin Hematoxylin (Hydroxybrazilin) is a compound that forms strongly colored complexes with certain metal ions, notably Fe(III) and Al(III) salts and a kind of stain in histology.
S3130 Biotin (Vitamin B7) Biotin(Vitamin B7) is a B-vitamin and acts as a necessary coenzyme for cell growth, the production of fatty acids, and the metabolism of fats and amino acids. Biotin is covalently attached to distinct lysine residues in histones, affecting chromatin structure and mediating gene regulation.
S4107 Clofazimine Clofazimine (NSC-141046) is a rhimophenazine dye, originally developed for the treatment of tuberculosis, it has both antimicrobial and antiinflammatory activity, postulated mechanisms of action include intercalation of clofazimine with bacterial DNA and increasing levels of cellular phospholipase A2.
S7764 WST-8 WST-8 is a water-soluble tetrazolium salt used for assessing cell metabolic activity that produces corresponding formazan dye that absorbs at 460 nm. WST-8 is typically used as a cell viability indicator in cell proliferation assays.
S7777 Coelenterazine Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. Renilla luciferase and substrate coelenterazine have been used as bioluminescence donors in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions. Coelenterazine is a superoxide anion-sensitive chemiluminescent probe, and it can also be used in the chemiluminescent detection of peroxynitrite.
S7763 D-Luciferin D-Luciferin is a popular bioluminescent substrate of luciferase in the presence of ATP, used in luciferase-based bioluminescence imaging and cell-based high-throughput screening applications. In an immunocompetent mouse model of ovarian cancer, the use of D-luciferin substrate and firefly luciferase preserves tumour-host immune interactions since bioluminescent imaging is a more sensitive indication of tumour growth than weight gain.
S4535 Methylene Blue Methylene Blue (Basic Blue 9, Tetramethylthionine chloride, methylthioninium chloride, CI-52015) is used as a dye in chromoendoscopy. It Inhibits tau filament formation with IC50 of 1.9μM. Also it inhibits soluble guanylyl cyclase.
S8269 CFSE Carboxyfluorescein succinimidyl ester (CFSE, 5(6)-Carboxyfluorescein diacetate succinimidyl ester, CFDA-SE, 5(6)-CFDA N-succinmidyl ester) is a fluorescent cell staining dye. CFSE is frequently used in cell proliferation assay and motility assays. CFSE is cell permeable and covalently couples, via its succinimidyl group, to intracellular molecules, notably, to intracellular lysine residues and other amine sources.
S3700 DHBP dibromide DHBP (1,1'-diheptyl-4,4'-bipyridinium), a viologen for electrochromic memory display agent, inhibits the calcium release induced by 2 mM caffeine and 2 μg/ml polylysine with an IC50 value of 5 μg/ml and 4 μg/ml respectively.
S3876 Indigo Indigo (Indigotin) dye is an organic compound with a distinctive blue color. It is extracted from the leaves of certain plants or synthetic.
S5110 Safflower Yellow Safflower Yellow (Safflor Yellow, SY), the main active constituent of the traditional Chinese medicine Safflower, is known as a neuroprotective agent that indirectly attenuates neuroinflammation.
S4780 7-Methoxy-4-methylcoumarin 7-Methoxy-4-methylcoumarin is a coumarin derivative and fluorescent label. 7-Methoxy-4-methylcoumarin has an antimicrobial activitiy against both gram positive and gram negative bacterial stains. 4-Methylherniarin displays good activity against B. subtilis and S.sonnei with IC50 of 11.76 μg/ml and 13.47 μg/ml, respectively.
S5283 TMB-PS TMB-PS (TMBZ-PS, TetraMethyl BisPhenol S, Bis-(2,6dimethyl-4-hydroxyphenyl)-sulfone) is a chromogenic reagent for the detection of hydrogen peroxide e.g. in the enzymatic analysis of body fluids.
S5395 Phenolphthalein Phenolphthalein (Phthalimetten) is an acid-base pH indicator.
S5488 Fluorescein Fluorescein (Solvent Yellow 94, Resorcinolphthalein, Yellow fluorescein) is a manufactured organic compound and dye.
S5641 Rhodamine B Rhodamine B is used as a tracer dye in water to determine the rate and direction of flow and transport. It is a staining fluorescent dye used in fluorescence microscopy, flow cytometry, fluorescence correlation spectroscopy and ELISA in biotechnology fields.
S5656 Diphenylpyraline hydrochloride Diphenylpyraline hydrochloride is the hydrochloride salt form of diphenylpyraline, which is an antihistamine used in the treatment of allergic rhinitis, hay fever, and allergic skin disorders.
S6065 Congo Red Congo Red (Direct Red 28) is an indicator dye that is blue-violet at pH 3.0 and red at pH 5.0. It is an acid dye used in testing for hydrochloric acid in gastric contents but has carcinogenic properties.
S6101 Solvent Blue 35 Solvent Blue 35 (Sudan Blue II, Oil Blue 35) is a member of the Sudan family of hydrophobic fat-staining dyes, predominantly used for staining triglycerides in animal tissues (frozen sections).
S6165 Erythrosine B Erythrosine B is cherry or melon-pink synthetic, primarily used for food coloring.
S6191 Sudan I Sudan I (C.I. Solvent Yellow 14) is an azo dye. It causes tumors in the liver or urinary bladder in rats, mice, and rabbits and may be a potential carcinogen for humans.
S6580 D-Luciferin Potassium Salt D-luciferin is the natural substrate of the enzyme luciferase (Luc) which catalyzes the production of the typical yellow-green light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP.
S6718 MKT-077 MKT-077 (FJ-776) is a newly synthesized, highly water-soluble rhodacyanine dye that exhibits significant antitumor activity in a variety of model systems.
S0274 2-DI-1-ASP 2-Di-1-ASP (DASPI, 2M2PM, D 308, Compound 18a) is a mono-stryryl dye which can be used as a mitochondrial stain and a groove-binding fluorescent probe for G-quadruplex (G4) DNA.
S0310 1-Methyl-7-nitroisatoic anhydride (1M7) 1-methyl-7-nitroisatoic anhydride (1M7) is a commonly applied RNA-SHAPE electrophile for probing 2'-hydroxyl reactivity.
S0485 Hoechst 33342 .Hoechst 33342 (Pibenzimol, bisBenzimide H 33342, HOE 33342, HO342) is a membrane-permeant fluorescent stain that can stain live cells. Hoechst 33342 binds to adenine-thymine-rich regions of DNA in the minor groove and greatly increases the fluorescence. It allows easy visualization of the nucleus in interphase cells and chromosomes in mitotic cells.
S0486 Hoechst 34580 Hoechst 34580 (HOE 34580) is a cell-permeable blue fluorescent dye to stain DNA and nuclei. Hoechst 34580 is also a good candidate for treating the Alzheimer's disease by inhibiting amyloid beta (Aβ) formation with IC50 of 0.86 μM.
S6824 Lucigenin Lucigenin (NSC-151912, L-6868) is a fluoerscent probe that exhibits a bluish-green fluorescence in the presence of endogenously generated superoxide anion radicals and chloride in cells.
S6825 Thioflavine S Thioflavine S (Thioflavin S, Direct Yellow 7) is a fluorogenic compound which becomes fluorescent only after oxidation. Thioflavine S is used as a fluorescent histochemical marker of dense core senile plaques.Thioflavine S can bind to dense-core amyloid-β deposits.
S6819 Luminol Luminol (Diogenes reagent, 3-Aminophthalhydrazide) is a versatile chemical exhibiting chemiluminescence with a blue glow, when mixed with an appropriate oxidizing agent. Luminol is uesed in forensic investigations to detect trace amounts of blood at crime scenes and in biological researches to detect copper, iron, and cyanides, as well as specific proteins by western blot. Luminol recently displayes promising applications for the treatment of cancer in deep tissues.
S6821 Thiazolyl Blue Thiazolyl Blue (MTT, Tetrazolium bromide, Methylthiazolyldiphenyl-tetrazolium bromide, Methylthialazole Tetrazolium) is a cell-permeable and positively charged colorimetric agent that is widely used to detect reductive metabolism in cells and to measure cell proliferation, cytotoxicity, and apoptosis. Thiazolyl Blue (MTT) is reduced from yellow color to purple formazan in living cells.
S6818 Nile Red Nile Red (Nile Blue A oxazone, Phenoxazone 9) is an excellent vital fluorescent stain for the detection of intracellular lipid droplets in the presence of a hydrophobic environment. Nile Red is applied for staining intracellular lipids, hydrophobic domains of proteins and lysosomal phospholipid inclusions.
S6820 X-GAL X-GAL (BCIG) is a widely used chromogenic β-galactosidase substrate. β-galactosidase cleaves X-gal and produce an insoluble detectable blue compound. X-Gal is applied in blue-white selection of recombinant bacterial colonies with the lac+ genotype.
S6822 TMB dihydrochloride TMB dihydrochloride (3,3',5,5'-Tetramethylbenzidine dihydrochloride hydrate, TMB-d, BM blue, Sure Blue TMB) is an excellent colorimetric substrate for detection of horseradish peroxidase (HRP) labeled probes and is used in staining procedures in immunohistochemistry and in enzyme-linked immunosorbent assays (ELISA).
S6848 3'-Fluoro-3'-deoxythymidine (Alovudine) 3'-Fluoro-3'-deoxythymidine (Alovudine, CL 184824, FddThd, FLT, MIV-310) is a potent inhibitor of polymerase γ and reverse transcriptase that can be used in the treatment of HIV infection. 3'-Fluoro-3'-deoxythymidine (Alovudine) is also a marker of DNA synthesis that can be used as an early response biomarker in the chemotherapy of pancreatic cancer.
S6849 DFO DFO (9H-1,8-Diazafluoren-9-one) is a fluorochrome that is used in the forensic field to enhance latent fingerprints deposited on porous surfaces by reacting with the amino acids present in the papillary exudate.
S8914 2-NBDG 2-NBDG, a fluorescent deoxyglucose derivative, is a a marker for detecting glucose uptake and an indicaotr of cell viability.
S6872 Merbromin Merbromin (Mercurochrome), a xanthene dye and an antibacterial agent, is the first of a series of antiseptics that contained mercury, also is a mixed-type inhibitor of 3CLpro due to its ability of increasing the KM and decreasing the Kcat of 3CLpro.
S6873 Thioflavin T Thioflavin T (ThT, Thioflavine T, Basic Yellow 1) is a benzothiazole dye that exhibits enhanced fluorescence upon binding to amyloid fibrils and is commonly used to diagnose amyloid fibrils. Thioflavin T is found to exist as micelles at concentrations commonly used to monitor fibrils by fluorescence assay. The micelles of Thioflavin T bind to amyloid fibrils leading to enhancement of fluorescence emission.
S3217 Brilliant Blue G Brilliant Blue G (BBG) is a dye which is commonly used in laboratories to stain or quantify proteins.Brilliant Blue G is a potent non-competitive antagonist of P2X7 receptor with IC50 of 10.1 nM and 265 nM for rat P2X7 and human P2X7, respectively.
S9687 H2DCFDA (DCFH-DA) H2DCFDA (DCFH-DA) is a cell-permeable probe used to detect intracellular reactive oxygen species (ROS) production. It is de-esterified intracellularly and turns to highly fluorescent 2′,7′-dichlorofluorescein upon oxidation. It is used in sensitive and rapid quantitation of oxygen-reactive species in response to oxidative metabolism; microplate assay for detecting oxidative products in phagocytic cells, and quantitative multiwell myeloid differentiation assay.(Ex/Em=488/525 nm)
S6240 Sudan II Sudan II (Sudan Red II, Solvent Orange 7, Color Index No: 12140, C.I. 12140) is a lysochrome (fat-soluble dye) azo dye used for staining of triglycerides in frozen sections, and some protein bound lipids and lipoproteins on paraffin sections.
S0866 Diphenylterazine (DTZ) Diphenylterazine (DTZ), a synthetic coelenterazine analog, is a bioluminescence agent. Diphenylterazine alone yields very little background, leading to excellent signal-to-background ratios. Diphenylterazine treatment can track tumor growth in a xenograft NU/J mouse model.
S6924 D-Luciferin sodium salt D-Luciferin (D-(-)-Luciferin, Firefly luciferin) sodium salt is the natural substrate of luciferases that catalyze the production of light in bioluminescent insects.
S6890 Trypan Blue Trypan Blue (Visionblue, Diphenyl Blue, Direct Blue 14) is a colorimetric dye that stains dead cells with a blue color easily observed using light microscopy at low resolution.
S6792 Dihydroethidium

Dihydroethidium (DHE, HE, Hydroethidine, PD-MY 003) is a cell-permeable blue fluorogenic probe used for detecting intracellular superoxide radical anion.
S3141 Maleimide Maleimide exhibits fluorescence quenching ability and can be used for the specific detection of thiol analytes as fluorogenic probes. Maleimide is also used for production of antibody-drug conjugate (ADC) which is used in cancer research.
S3316 5-Hydroxy-1-tetralone

5-hydroxy-1-tetralone is a fluorescent labeling reagent for the determination of glycosphingolipid from small amounts of biological samples.
S9784 JC-1 JC-1 (CBIC2, NK 1420), a fluorescent lipophilic carbocyanine dye, is a mitochondrial potential (ΔΨ(m)) marker. JC-1 fluorescence is usually excited by the 488 nm laser wavelength common in flow cytometers.
S3577 Rhodamine 123 Rhodamine 123 (RH-123, R-22420) is a fluorescent cationic dye used to label mitochondria in living cells. Rhodamine 123 inhibits ADP-stimulated respiration of mitochondria with Ki = 12 μM and ATPase activity of inverted inner membrane vesicles with Ki of 126 μM and partially purified F1-ATPase with Ki of 177 μM.
S3593 Rhodamine 6G Rhodamine 6G (R6G, Basic Red 1, Rhodamine 590) is a fluorescence tracer that binds to mitochondria, thus reducing the intact mitochondria number and inhibiting mitochondrial metabolic activity.
S4418 Phenol Red sodium salt Phenol Red sodium salt (Phenolsulfonephthalein sodium salt) is used ubiquitously as a pH indicator in tissue culture media ranging from 6.8 (yellow) to 8.2 (red). Phenol red binds to the estrogen receptor of MCF-7 human breast cancer cells.
S4424 Hyaluronidase Hyaluronidase (Hyaluronate 4-glycanohydrolase, Hyaluronoglucosaminidase, Amphadase, Hydase, Vitrase) is a naturally occurring enzyme that degrades hyaluronic acid, which constitutes an essential part of the extracellular matrix. It depolymerizes hyaluronic acid by cleavage of glycosidic bonds and has been utilized in ophthalmic surgery.
S4498 Oil Red O Oil red O (ORO) is a commonly used dye for the tissue staining, which recognizes nitroglycerin and cholesterol esters. Oil red O can be fluorescently lighted up upon meeting dsDNA with emission peak localized at 600 nm, although it almost does not fluoresce by itself.
S4497 Ponceau S Ponceau S (Acid Red 112) is the most commonly used stain for immunoblotting protocols. Ponceau S dye is applied as an acidic aqueous solution, and the proteins on the membrane are stained with red color.
S5975 Calcein Calcein (Fluorexon) is a fluorescent fluid phase marker used to track and visualize cellular processes such as synaptic vesicle fusion. Calcein is also the fluorophore for live cells in the commonly used Live/Dead viability assay. (Calcein itself cannot penetrate the cell membrane and cannot be directly applied in experiments assessing live cells. In practice, Calcein AM is employed, which can enter cells and be hydrolyzed by intracellular enzymes, releasing the fluorescent Calcein compound, thereby achieving the labeling of live cells.)
S5974 Alizarin Red S Alizarin Red S sodium (Alizarin red S mono sodiumsalt, ARS sodium, C.I. Mordant Red 3, C.I 58005, Alizarin Carmine, Alizarin Red, Alizarin sodium monosulfonate, Alizarin sulfonate sodium, Alizarinsulfonic acid sodium salt, Sodium alizarinsulfonate) is an anthraquinone dye that has been used to evaluate calcium-rich deposits by cells in culture.
S5976 Sulforhodamine B sodium salt Sulforhodamine B (SRB, Acid Red 52, Kiton Red 620) sodium salt is a protein-specific fluorescent dye that is utilized to quantitate cell expansion, growth, and migration.
S9886 Biocytin Biocytin ((+)-Biocytin, Biotinyl-L-lysine) is a conjugate of D-biotin and L-lysine. Biocytin is an attractive neuronal tracer. It labels neurons fast over long distances, and it can be used in conjunction with calcium dyes to report on neuronal activity in retrogradely labeled live neurons.
S6928 Fluorescein-5-isothiocyanate (FITC) Fluorescein-5-isothiocyanate (FITC, Fluorescein isothiocyanate isomer I, 5-FITC) is a fluorescent probe capable of being conjugated to tissue and proteins.