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Macrocyclic Compound Library

Catalog No.L7300

A unique collection of 184 macrocyclic compounds used for high throughput screening(HTS) and high content screening(HCS).

96 well plates

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Cited by 279 Publications

Macrocyclic Compound Library Contents

Description & Advantages

•Macrocycles are often described as molecules and ions containing twelve or more membered ring. Macrocycles often bind ions and facilitate ion transport across hydrophobic membranes and solvents.Macrocycles are often bioactive and could be useful for drug delivery
 
•A unique collection of 184 macrocyclic compounds used for high throughput screening(HTS) and high content screening(HCS)
 
•Some compounds have been approved by the FDA
 
•Structurally diverse,medicinally active,and cell permeable
 
•Rich documentation with structure and bioactivity information
 
•NMR and HPLC validated to ensure high purity

Product Details

Formulation 165 compounds pre-dissolved in 10mM DMSO, 18 compounds pre-dissolved in 10mM water and 1 compounds pre-dissolved in 2mM water
Container 96 Deep Well Plate Sealed With Aluminum Foil
Stability 12 months -20°C in DMSO
24 months -80°C in DMSO
Shipping Blue ice or dry ice

Case Studies using Selleck Compound Libraries

  • Application of GPCR Compound Library in liver cancer (This article was published in Nature (IF=43) and took about 15 months):

    Nature.2019;574(7777):268-272

  • Application of Kinase Inhibitor Library in colorectal cancer (This article was published in Nature Communications (IF=11) and took about 8 months):

    Nat Commun. 2019 16;10(1):2197

  • Application of FDA-approved Drug Library in antivirus (This article was published in Cell Research (IF=17) and took about 13 months):

    Cell Res. 2019;29(9):739-753

  • Application of FDA-approved Drug Library in metabolism (This article was published in Movement Disorders (IF=8) and took about 10 months):

    Mov Disord. 2019;34(3):323-334

  • Application of Epigenetics Compound Library in acute lymphoblastic leukemia (This article was published in Blood (IF=16) and took about 16 months):

    Blood. 2019 17;134(16):1323-1336

  • Application of Inhibitor Library in tumor immunology (This article was published in Cancer Immunol Res (IF=8.6) and took about 12 months):

    Cancer Immunol Res.2017;5(9):790-803

Macrocyclic Compound Library Composition

HTS Facility Partners