Covalent Inhibitor Library

Catalog No.L5800

A unique collection of 843 covalent inhibitors or small molecule compounds with covalently reactive groups

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Cited by 279 Publications

•A unique collection of 843 covalent inhibitors or small molecule compounds with covalently reactive groups

•Covalent inhibitors have excellent pharmacokinetic characteristics,and can overcome the resistance generated by mutations

•Some covalent inhibitors have been approved by the FDA

•Structurally diverse, medicinally active, and cell permeable

•Rich documentation with structure, IC50, and customer reviews

•NMR and HPLC validated to ensure high purity

Formulation	798 compounds pre-dissolved in 10mM DMSO, 30 compounds pre-dissolved in 10mM water and 15 compounds pre-dissolved in 2mM DMSO
Container	96 Deep Well Plate Sealed With Aluminum Foil
Stability	12 months	-20°C	in DMSO
Stability	24 months	-80°C	in DMSO
Shipping	Blue ice or dry ice

Application of GPCR Compound Library in liver cancer (This article was published in Nature (IF=43) and took about 15 months):

Nature.2019;574(7777):268-272
Application of Kinase Inhibitor Library in colorectal cancer (This article was published in Nature Communications (IF=11) and took about 8 months):

Nat Commun. 2019 16;10(1):2197
Application of FDA-approved Drug Library in antivirus (This article was published in Cell Research (IF=17) and took about 13 months):

Cell Res. 2019;29(9):739-753
Application of FDA-approved Drug Library in metabolism (This article was published in Movement Disorders (IF=8) and took about 10 months):

Mov Disord. 2019;34(3):323-334
Application of Epigenetics Compound Library in acute lymphoblastic leukemia (This article was published in Blood (IF=16) and took about 16 months):

Blood. 2019 17;134(16):1323-1336
Application of Inhibitor Library in tumor immunology (This article was published in Cancer Immunol Res (IF=8.6) and took about 12 months):

Cancer Immunol Res.2017;5(9):790-803