Home Peptide Products tat-nr2b9c For research use only. Not for use in humans.

tat-nr2b9c

Amino-acid Sequence

Amino-acid Sequence

CAS No. 500992-11-0

Purity & Quality Control

Batch: P122001 DMSO] 100 mg/mL] false] Water] 100 mg/mL] false] Ethanol] Insoluble] false Purity: 98.02%
98.02

Introduction

Tat-NR2B9c (Tat-NR2Bct, NA-1) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively, and disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 μM and 8 μM, respectively, also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy.

Product Information

Molecular Formula:

C105H188N42O30
Molecular Weight: 2518.88
CAS No.: 500992-11-0
Appearance: White Powder
Peptide Content (by %N): ≥80%
Single Impurity (by HPLC): ≤1.0%
Assay (By Anhydrous, Acetic Acid-free): 95.0~105.0%
MS: Consistent
Packing: plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
Storage
(From the date of receipt):		 3 years-20°C powder
Shipping: Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)