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Famciclovir

Name: Famciclovir
Brand: Selleck Chemicals
SKU: S2467
Rating: 5 (10 reviews)

Synonyms: BRL-42810

Catalog No.S2467 Purity: 99.98%

Famciclovir (BRL-42810) is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections.

Famciclovir Chemical Structure

CAS: 104227-87-4

Selleck's Famciclovir has been cited by 10 publications

Purity & Quality Control

Batch: S246701 DMSO] 64 mg/mL] false] Water] 64 mg/mL] false] Ethanol] 48 mg/mL] false Purity: 99.98%

99.98

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Biological Activity

Description	Famciclovir (BRL-42810) is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-01-11)
NCT05283551	Recruiting	Multiple Sclerosis	Queen Mary University of London	November 25 2020	Phase 2
NCT00878072	Completed	Herpes Labialis	Novartis Pharmaceuticals\|Novartis	March 25 2009	Phase 2\|Phase 3
NCT01154543	Completed	HIV Positive\|Herpes Simplex Genital	Holdsworth House Medical Practice	March 2008	--
NCT00448227	Completed	Herpes Simplex	Novartis	October 2007	Phase 2
NCT00098059	Completed	Herpes Simplex	Novartis Pharmaceuticals\|Novartis	February 2005	Phase 3

Chemical lnformation & Solubility

Molecular Weight	321.33863	Formula	C₁₄H₁₉N₅O₄
CAS No.	104227-87-4	SDF	Download Famciclovir SDF
Smiles	CC(=O)OCC(CCN1C=NC2=CN=C(N=C21)N)COC(=O)C
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 64 mg/mL ( (199.16 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 64 mg/mL

Ethanol : 48 mg/mL

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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