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Hydrochlorothiazide

Name: Hydrochlorothiazide
Brand: Selleck Chemicals
SKU: S1708
Rating: 5 (1 reviews)

Catalog No.S1708 Purity: 99.86%

Hydrochlorothiazide is a first line diuretic compound of the thiazide class.

Hydrochlorothiazide Chemical Structure

CAS: 58-93-5

Selleck's Hydrochlorothiazide has been cited by 1 publication

Purity & Quality Control

Batch: S170801 0.5MNAOH] 3 mg/mL] false] DMSO] 0 mg/mL] false] Water] 0 mg/mL] false Purity: 99.86%

99.86

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Biological Activity

Description	Hydrochlorothiazide is a first line diuretic compound of the thiazide class.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-01-11)
NCT04964050	Withdrawn	Healthy Volunteers	GlaxoSmithKline	April 21 2022	Phase 1
NCT05040880	Completed	Hypertension	HK inno.N Corporation	July 8 2021	Phase 1
NCT06083116	Completed	Diabetes in Adults	Jiangsu HengRui Medicine Co. Ltd.	August 28 2019	Phase 1
NCT04197622	Completed	Healthy Volunteers	Parc de Salut Mar	March 5 2019	Phase 1

Chemical lnformation & Solubility

Molecular Weight	297.74	Formula	C₇H₈ClN₃O₄S₂
CAS No.	58-93-5	SDF	Download Hydrochlorothiazide SDF
Smiles	C1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

0.5MNAOH : 3 mg/mL

DMSO : 0 mg/mL ( (0.0 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 0 mg/mL

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
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