Home Transmembrane Transporters Sodium Channel inhibitor Phenytoin For research use only.

Phenytoin

Synonyms: Di-Hydan, Dihycon, Dilabid, Diphedan, Diphenat, Diphenylan, Diphenylhydantoin, Hydantol, Lehydan, NSC 8722

Phenytoin (Di-Hydan, Dihycon, Dilabid, Diphedan, Diphenat, Diphenylan, Diphenylhydantoin, Hydantol, Lehydan, NSC 8722) is an inactive voltage-gated sodium channel stabilizer.

Phenytoin Chemical Structure

Phenytoin Chemical Structure

CAS: 57-41-0

Selleck's Phenytoin has been cited by 2 publications

Purity & Quality Control

Batch: Purity: 99.91%
99.91

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Biological Activity

Description Phenytoin (Di-Hydan, Dihycon, Dilabid, Diphedan, Diphenat, Diphenylan, Diphenylhydantoin, Hydantol, Lehydan, NSC 8722) is an inactive voltage-gated sodium channel stabilizer.
Targets
Sodium channel [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06067412 Completed Status Epilepticus Shaheed Zulfiqar Ali Bhutto Medical University August 1 2022 Not Applicable
NCT04647877 Completed Chronic Idiopathic Axonal Polyneuropathy David J. Kopsky|Princess Beatrix Muscle Foundation|Dr. C.J. Vaillant Fonds|UMC Utrecht September 17 2020 Phase 2|Phase 3
NCT04829838 Unknown status Status Epilepticus ayesha tariq|King Edward Medical University July 25 2019 Phase 4
NCT01635829 Completed Healthy Participants Janssen Infectious Diseases BVBA May 2012 Phase 1
NCT01478035 Terminated Seizures|Pneumococcal Meningitis M. Carmen Cabellos Minguez|Hospital Universitari de Bellvitge|Hospital Vall d''Hebron|Germans Trias i Pujol Hospital|Hospital Clinic of Barcelona|Fundació Institut de Recerca de l''Hospital de la Santa Creu i Sant Pau|Hospitales Universitarios Virgen del Rocío|Hospital Universitario La Paz|Hospital Universitario Ramon y Cajal|Hospital Juan Canalejo|Hospital Mutua de Terrassa|Hospital Universitario Virgen Macarena November 2011 Phase 4

Chemical lnformation & Solubility

Molecular Weight 252.27 Formula

C15H12N2O2
CAS No. 57-41-0 SDF Download Phenytoin SDF
Smiles C1=CC=C(C=C1)C2(C(=O)NC(=O)N2)C3=CC=CC=C3
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 50 mg/mL ( (198.2 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 13 mg/mL

Water : Insoluble


Molecular Weight Calculator

In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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