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Tobramycin

Name: Tobramycin
Brand: Selleck Chemicals
SKU: S2514
Rating: 5 (1 reviews)

Synonyms: NSC 180514,Deoxykanamycin B, Nebramycin Factor 6

Catalog No.S2514 Purity: 99.87%

Tobramycin (NSC 180514,Deoxykanamycin B, Nebramycin Factor 6) is an aminoglycoside antibiotic with an IC50 of 9.7 μM.

Tobramycin Chemical Structure

CAS: 32986-56-4

Selleck's Tobramycin has been cited by 1 publication

Purity & Quality Control

Batch: Purity: 99.87%

99.87

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Biological Activity

Description	Tobramycin (NSC 180514,Deoxykanamycin B, Nebramycin Factor 6) is an aminoglycoside antibiotic with an IC50 of 9.7 μM.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-01-11)
NCT06016088	Not yet recruiting	Cystic Fibrosis Lung\|Respiratory Infections Recurrent Chronic\|Pseudomonas Aeruginosa	Respirion Pharmaceuticals Pty Ltd	December 2023	Phase 1\|Phase 2
NCT05169229	Recruiting	Arthroplasty Replacement Hip\|Osteoarthritis Hip\|Antibiotic Resistant Infection\|Prosthetic Joint Infection	University Hospital Linkoeping\|Region Östergötland\|The Swedish Research Council	April 1 2022	Phase 2\|Phase 3
NCT04964947	Recruiting	Wound Infection\|Fractures Open\|Surgical Site Infection	Massachusetts General Hospital\|United States Department of Defense	January 10 2022	Phase 3
NCT04297631	Completed	Antibotics in Cementless Knees	Washington University School of Medicine	February 14 2020	Phase 4
NCT03904836	Completed	Renal Dialysis\|Renal Failure Chronic	Maisonneuve-Rosemont Hospital	January 31 2019	Phase 1

Chemical lnformation & Solubility

Molecular Weight	467.52369	Formula	C₁₈H₃₇N₅O₉
CAS No.	32986-56-4	SDF	Download Tobramycin SDF
Smiles	C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(CC(C(O3)CN)O)N)N
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

Water : 94 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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