ALKBH5 inhibitor 2 (Cpd 20m)

Name: ALKBH5 inhibitor 2 (Cpd 20m)
Brand: Selleck Chemicals
SKU: E1638

Catalog No.E1638 Purity: 99%

ALKBH5 inhibitor (Cpd 20m) is a potent and selective inhibitor of RNA m6A demethylase AlkB homolog 5 ALKBH5 with IC50 of 21 nM.

ALKBH5 inhibitor 2 (Cpd 20m) Chemical Structure

CAS:

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Biological Activity

Description	ALKBH5 inhibitor (Cpd 20m) is a potent and selective inhibitor of RNA m6A demethylase AlkB homolog 5 ALKBH5 with IC50 of 21 nM.

References

[1] Fang Z, et al. Eur J Med Chem. 2022 Aug 5:238:114446.

Chemical lnformation & Solubility

Molecular Weight	351	Formula	C₁₅H₁₇N₃O₅S
CAS No.		SDF	Download ALKBH5 inhibitor 2 (Cpd 20m) SDF
Storage (From the date of receipt)	3 years-20°Cpowder	Solutions are unstable. Prepare fresh or purchase small, pre-packaged sizes. Repackage upon receipt.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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