Home Neuronal Signaling AChR antagonist Atropine For research use only.

Atropine

Atropine (Atropen, Atnaa, Tropine tropate, DL-Hyoscyamine) is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with anti-myopia effect.

Atropine Chemical Structure

Atropine Chemical Structure

CAS: 51-55-8

Selleck's Atropine has been cited by 1 publication

Purity & Quality Control

Batch: Purity: 99.64%
99.64

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Biological Activity

Description Atropine (Atropen, Atnaa, Tropine tropate, DL-Hyoscyamine) is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with anti-myopia effect.
Targets
mAChR [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06102382 Not yet recruiting Cesarean Section|Hypotension|Norepinephrine Assiut University December 10 2023 Not Applicable
NCT06162390 Recruiting Thyroidectomy Kyungpook National University Chilgok Hospital November 20 2023 Not Applicable
NCT06082856 Recruiting Anesthesia|Dexmedetomidine|Hemodynamics|Ambulatory Care Centre Hospitalier Universitaire de Nīmes October 19 2023 Not Applicable

Chemical lnformation & Solubility

Molecular Weight 289.37 Formula

C17H23NO3
CAS No. 51-55-8 SDF --
Smiles CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 58 mg/mL ( (200.43 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 58 mg/mL

Water : Insoluble


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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