Penicillin G Sodium

Synonyms: Benzylpenicillin Sodium

Penicillin G Sodium (Benzylpenicillin) is a β-lactam antibiotic produced by Penicillin spp.

Penicillin G Sodium Chemical Structure

Penicillin G Sodium Chemical Structure

CAS: 69-57-8

Selleck's Penicillin G Sodium has been cited by 2 publications

Purity & Quality Control

Batch: S416001 DMSO] 71 mg/mL] false] Water] 71 mg/mL] false] Ethanol] 1 mg/mL] false Purity: 98.77%
98.77

Choose Selective Antibiotics for Mammalian Cell Culture Inhibitors

Biological Activity

Description Penicillin G Sodium (Benzylpenicillin) is a β-lactam antibiotic produced by Penicillin spp.
In vitro
In vitro Benzylpenicillin is also commonly known as penicillin G. Benzylpenicillin exhibits activity mainly against Gram-positive organisms. Some Gram-negative organisms such as Neisseria gonorrhoeae and Neisseria meningitidis are also reported to be susceptible to Penicillin G.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04647331 Recruiting Infective Endocarditis Uppsala University June 1 2021 --
NCT03612557 Completed Healthy Pfizer August 20 2018 Phase 1
NCT00789217 Completed Penicillin Allergy Chulalongkorn University|Mahidol University December 2008 Not Applicable

Chemical lnformation & Solubility

Molecular Weight 356.37 Formula

C16H18N2O4S.Na

CAS No. 69-57-8 SDF Download Penicillin G Sodium SDF
Smiles CC1(C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CC=C3)C(=O)[O-])C.[Na+]
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 71 mg/mL ( (199.23 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 71 mg/mL

Ethanol : 1 mg/mL


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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