Home GPCR & G Protein CCK receptor agonist Caerulein (FI-6934) For research use only.

Caerulein (FI-6934)

Synonyms: Ceruletide, Cerulein

Caerulein (Ceruletide, Cerulein, FI-6934), a cholecystokinin (CCK) receptor agonist, is a safe and effective cholecystokinetic agent and small bowel and exocrine pancreatic stimulant.

Caerulein (FI-6934) Chemical Structure

Caerulein (FI-6934) Chemical Structure

CAS: 17650-98-5

Purity & Quality Control

Batch: Purity: 99.94%
99.94

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Biological Activity

Description Caerulein (Ceruletide, Cerulein, FI-6934), a cholecystokinin (CCK) receptor agonist, is a safe and effective cholecystokinetic agent and small bowel and exocrine pancreatic stimulant.
Targets
CCK receptor [2]
In Vivo
In vivo

Low doses of the cholecystokinin agonists caerulein (0.00001 and 0.0001 mg/kg) elicits reduction of the nalaxone-induced jumping. The inhibition of jumping induced by caerulein is reduced with the selective cholecystokinin antagonists MK-329 and L-365,260. It is concluded that cholecystokinin mechanism(s) may be involved in its dependence, that the agonists may act on a presynaptic receptors.[2]

Chemical lnformation & Solubility

Molecular Weight 1352.40 Formula

C58H73N13O21S2
CAS No. 17650-98-5 SDF --
Smiles CSCCC(NC(=O)C(CC1=C[NH]C2=C1C=CC=C2)NC(=O)CNC(=O)C(NC(=O)C(CC3=CC=C(O[S](O)(=O)=O)C=C3)NC(=O)C(CC(O)=O)NC(=O)C(CCC(N)=O)NC(=O)C4CCC(=O)N4)C(C)O)C(=O)NC(CC(O)=O)C(=O)NC(CC5=CC=CC=C5)C(N)=O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 100 mg/mL ( (73.94 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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