Ceftazidime

Synonyms: GR20263

Ceftazidime(GR20263) is a third-generation cephalosporin that has activity against Gram-negative bacilli, including Pseudomonas aeruginosa.

Ceftazidime Chemical Structure

Ceftazidime Chemical Structure

CAS: 72558-82-8

Selleck's Ceftazidime has been cited by 3 publications

Purity & Quality Control

Batch: Purity: 99.88%
99.88

Choose Selective Selection Antibiotics for Transfected Cell Inhibitors

Biological Activity

Description Ceftazidime(GR20263) is a third-generation cephalosporin that has activity against Gram-negative bacilli, including Pseudomonas aeruginosa.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06089668 Recruiting Melioidosis AN2 Therapeutics Inc|Mahidol Oxford Tropical Medicine Research Unit November 1 2023 --
NCT05487586 Recruiting Hospital Acquired Pneumonia|Ventilator Acquired Pneumonia|Complicated Intra Abdominal Infections Pfizer October 20 2022 --
NCT05413343 Recruiting Severe Sepsis First Affiliated Hospital of Zhejiang University January 1 2022 --
NCT04927312 Completed Complicated Intra-abdominal Infection Pfizer October 1 2021 Phase 3
NCT04628572 Completed Gram Negative Infections Pfizer January 29 2021 --

Chemical lnformation & Solubility

Molecular Weight 546.58 Formula

C22H22N6O7S2

CAS No. 72558-82-8 SDF Download Ceftazidime SDF
Smiles CC(C)(C(=O)O)ON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C[N+]4=CC=CC=C4)C(=O)[O-]
Storage (From the date of receipt)

In vitro
Batch:

Water : 100 mg/mL

DMSO : 4 mg/mL ( (7.31 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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