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Creatinine

Synonyms: NSC13123

Creatinine(NSC13123) is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.

Creatinine Chemical Structure

Creatinine Chemical Structure

CAS: 60-27-5

Purity & Quality Control

Batch: S310201 Water] 23 mg/mL] false] DMSO] Insoluble] false] Ethanol] Insoluble] false Purity: 99.90%
99.90

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Biological Activity

Description Creatinine(NSC13123) is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.
In vitro
In vitro

Creatinine is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body. Creatinine levels in blood and urine may be used to calculate the creatinine clearance (CrCl), which reflects the glomerular filtration rate (GFR), an important clinical index of renal function.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04598516 Withdrawn Acute Kidney Injury (Nontraumatic)|Contrast-induced Nephropathy|Renal Insufficiency Maastricht University Medical Center November 1 2097 --
NCT04597892 Withdrawn Renal Insufficiency|Acute Kidney Injury|Contrast-induced Nephropathy Maastricht University Medical Center May 1 2097 --
NCT05847179 Not yet recruiting Werner Syndrome PRG Science & Technology Co. Ltd. January 1 2025 Phase 2
NCT05432765 Not yet recruiting Kidney Transplant Rejection University of Florida December 2024 Early Phase 1
NCT06120569 Not yet recruiting Diabetic Kidney Disease Nora Hussein Kamal|Assiut University September 18 2024 Not Applicable
NCT04589065 Suspended Heart Failure|Chronic Systolic Heart Failure|Renal Failure|Cardiorenal Syndrome Lenar Yessayan|University of Michigan September 2024 Not Applicable

Chemical lnformation & Solubility

Molecular Weight 113.12 Formula

C4H7N3O
CAS No. 60-27-5 SDF Download Creatinine SDF
Smiles CN1CC(=O)N=C1N
Storage (From the date of receipt)

In vitro
Batch:

Water : 23 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble


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In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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