Home Neuronal Signaling 5-HT Receptor antagonist Cyclobenzaprine HCl For research use only.

Cyclobenzaprine HCl

Synonyms: Cyclobenzaprine hydrochloride

Cyclobenzaprine HCl(Cyclobenzaprine hydrochloride) is a muscle relaxant by blocking pain sensations, used for the treatment of muscle spasms; A 5-HT2 receptor antagonist.

Cyclobenzaprine HCl Chemical Structure

Cyclobenzaprine HCl Chemical Structure

CAS: 6202-23-9

Purity & Quality Control

Batch: S428301 DMSO] 62 mg/mL] false] Water] 62 mg/mL] false] Ethanol] 62 mg/mL] false Purity: 99.97%
99.97

Other 5-HT Receptor Products

Related compound libraries

Choose Selective 5-HT Receptor Inhibitors

Biological Activity

Description Cyclobenzaprine HCl(Cyclobenzaprine hydrochloride) is a muscle relaxant by blocking pain sensations, used for the treatment of muscle spasms; A 5-HT2 receptor antagonist.
Targets
5-HT2 receptor [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03700970 Completed Breast Reconstruction|Anesthesia|Transverse Abdominis Plane Block Vanderbilt University Medical Center June 13 2019 Phase 4
NCT03443960 Completed Healthy Subjects Tonix Pharmaceuticals Inc. January 29 2018 Phase 1
NCT03168022 Completed Healthy Adults Tonix Pharmaceuticals Inc. December 16 2015 Phase 1
NCT01921296 Terminated Sleep Initiation and Maintenance Disorders|Pain Lynn Henry|Damon Runyon Cancer Research Foundation|University of Michigan Rogel Cancer Center August 2013 Phase 2

Chemical lnformation & Solubility

Molecular Weight 311.85 Formula

C20H22ClN
CAS No. 6202-23-9 SDF Download Cyclobenzaprine HCl SDF
Smiles CN(C)CCC=C1C2=CC=CC=C2C=CC3=CC=CC=C31.Cl
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 62 mg/mL ( (198.81 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 62 mg/mL

Ethanol : 62 mg/mL


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

Please enter your name.
Please enter your email. Please enter a valid email address.
Please write something to us.
Tags: buy Cyclobenzaprine HCl | Cyclobenzaprine HCl supplier | purchase Cyclobenzaprine HCl | Cyclobenzaprine HCl cost | Cyclobenzaprine HCl manufacturer | order Cyclobenzaprine HCl | Cyclobenzaprine HCl distributor