Home Biosimilar Antibodies NF-κB NF-κB Denosumab (anti-RANK ligand) For research use only.
Not for use in humans.

Denosumab (anti-RANK ligand)

Synonyms: AMG-162, Prolia, Xgeva

Denosumab (anti-RANK ligand) (AMG-162, Prolia, Xgeva) is a fully human monoclonal antibody that selectively inhibits primate RANKL. Denosumab inhibits the ability of human RANKL (143–317) to stimulate the formation of osteoclasts derived from murine RAW 264.7 cells with an IC50 value of 1.64 nM.

Denosumab (anti-RANK ligand)

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Selleck's Denosumab (anti-RANK ligand) has been cited by 1 Publication

Purity & Quality Control

Batch: Purity: 99.68% Protein concentration: 5mg/ml Endotoxin Level: <1EU/mg
99.68

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Biological Activity

Description Denosumab (anti-RANK ligand) (AMG-162, Prolia, Xgeva) is a fully human monoclonal antibody that selectively inhibits primate RANKL. Denosumab inhibits the ability of human RANKL (143–317) to stimulate the formation of osteoclasts derived from murine RAW 264.7 cells with an IC50 value of 1.64 nM.

Product Details

CAS No. 615258-40-7
Isotype human IgG4
Source HEK293
Formulation PBS Buffer, pH 7.4
Storage
(From the date of receipt)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.

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