Home Biosimilar Antibodies Protein Tyrosine Kinase EGFR inhibitor Depatuxizumab mafodotin For research use only.
Not for use in humans.

Depatuxizumab mafodotin

Synonyms: ABT-414, Depatux-M

Depatuxizumab Mafodotin (Depatux-M, ABT-414) is an antibody-drug conjugate consisting of an EGFR IGg1 monoclonal antibody conjugated to the tubulin inhibitor monomethyl auristatin F via a stable maleimidocaproyl link. Depatuxizumab Mafodotin is used in the treatment of recurrent EGFR-amplified Glioblastoma (GBM).

Depatuxizumab mafodotin

CAS No. 1585973-65-4

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Purity & Quality Control

Batch: D404201 Purity: 98.38% Protein concentration: 5.52mg/ml Endotoxin Level: ＜1EU/mg
98.38

Choose Selective EGFR Inhibitors

Biological Activity

Description Depatuxizumab Mafodotin (Depatux-M, ABT-414) is an antibody-drug conjugate consisting of an EGFR IGg1 monoclonal antibody conjugated to the tubulin inhibitor monomethyl auristatin F via a stable maleimidocaproyl link. Depatuxizumab Mafodotin is used in the treatment of recurrent EGFR-amplified Glioblastoma (GBM).

Product Details

CAS No. 1585973-65-4
ADC antiody Depatuxizumab
ADC linker Maleimidocaproyl (mc) linker
ADC cytotoxin MMAF
Formulation 1xPBS
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

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