Home Proteases HIV Protease inhibitor Dextran sulfate sodium (DSS) For research use only.

Dextran sulfate sodium (DSS)

Synonyms: Dextran sulfate sodium salt

Dextran sulfate sodium (DSS) is a potent and selective inhibitor of human immunodeficiency virus type 1 (HIV-1) in vitro that inhibits virus adsorption to the host cells.

Dextran sulfate sodium (DSS) Chemical Structure

Dextran sulfate sodium (DSS) Chemical Structure

CAS: 9011-18-1

Purity & Quality Control

Batch: Purity: 99%
99

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Biological Activity

Description Dextran sulfate sodium (DSS) is a potent and selective inhibitor of human immunodeficiency virus type 1 (HIV-1) in vitro that inhibits virus adsorption to the host cells.
Targets
HIV-1 [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06164704 Recruiting Chronic Rhinosinusitis With Nasal Polyps Upstream Bio Inc. December 18 2023 Phase 2
NCT06111846 Not yet recruiting Autoimmune Pulmonary Alveolar Proteinosis Jiuzhitang Maker (Beijing) Cell Technology Co.Ltd.|The First Affiliated Hospital of Guangzhou Medical University November 1 2023 Phase 2
NCT05668390 Not yet recruiting Allergic Rhinoconjunctivitis|Birch Pollen Allergy Stallergenes Greer October 1 2023 Phase 3

Chemical lnformation & Solubility

Molecular Weight 36-50Kda Formula
CAS No. 9011-18-1 SDF --
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

Water : 100 mg/mL

DMSO : 50 mg/mL ( ； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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