Home Biosimilar Antibodies Protein Tyrosine Kinase HER2 -EGFR chemical Disitamab vedotin For research use only.
Not for use in humans.

Disitamab vedotin

Synonyms: RC-48, RC 480-ADC

Disitamab Vedotin (RC-48 ,RC 480-ADC) is an antibody-drug conjugate(ADC) composed of anti-[ERBB2 (epidermal growth factor receptor 2, receptor tyrosine-protein kinase erbB-2, EGFR2, HER2, HER-2, p185c-erbB2, NEU, CD340)] humanized monoclonal antibody, conjugated to monomethylauristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Disitamab Vedotin has the potential for use in solid tumors mainly in advanced breast cancer.

Disitamab vedotin

CAS No. 2136633-23-1

Click to purchase the isotype control of Disitamab vedotin

Purity & Quality Control

Batch: D404901 Purity: 99.17% Protein concentration: 3.3mg/ml Endotoxin Level: ＜1EU/mg
99.17

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Biological Activity

Description Disitamab Vedotin (RC-48 ,RC 480-ADC) is an antibody-drug conjugate(ADC) composed of anti-[ERBB2 (epidermal growth factor receptor 2, receptor tyrosine-protein kinase erbB-2, EGFR2, HER2, HER-2, p185c-erbB2, NEU, CD340)] humanized monoclonal antibody, conjugated to monomethylauristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Disitamab Vedotin has the potential for use in solid tumors mainly in advanced breast cancer.

Product Details

CAS No. 2136633-23-1
DAR 3.8
ADC antiody Disitamab
ADC cytotoxin MMAE
Formulation 1xPBS
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

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