Home Biosimilar Antibodies Stem Cells & Wnt TGF-beta/Smad antibody Elezanumab (Anti-RGMA) For research use only.
Not for use in humans.

Elezanumab (Anti-RGMA)

Synonyms: ABT-555, AE12-1Y-QL

Elezanumab (Anti-RGMA) is a human monoclonal antibody that selectively targets repulsive guidance molecule A (RGMa). Elezanumab potently inhibited RGMa mediated BMP signalling via the SMAD1/5/8 pathway with IC50 of 97 pM. MW: 146.44 kD.

Elezanumab (Anti-RGMA)

Purity & Quality Control

≥99

Choose Selective TGF-beta/Smad Inhibitors

Biological Activity

Description Elezanumab (Anti-RGMA) is a human monoclonal antibody that selectively targets repulsive guidance molecule A (RGMa). Elezanumab potently inhibited RGMa mediated BMP signalling via the SMAD1/5/8 pathway with IC50 of 97 pM. MW: 146.44 kD.

Product Details

CAS No. 1791416-49-3
Molecular Weight 146.44 kDa
Isotype Human IgG1
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100mMPro-Ac,20mMArg-Ac，pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

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