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Elotuzumab (anti-SLAMF7)

Synonyms: BMS-901608, PDL063, HuLuc63

Catalog No.A2034 Purity: 99%

Elotuzumab (anti-SLAMF7, BMS-901608, PDL063, HuLuc63) is a humanized monoclonal antibody that binds human signaling lymphocytic activation molecule F7 (hSLAMF7, also known as CS1, CD319, or CRACC). Elotuzumab shows a dual mechanism of action that includes the direct activation of natural killer (NK) cells and the induction of NK cell–mediated antibody-dependent cellular cytotoxicity.

Elotuzumab (anti-SLAMF7)

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Selleck's Elotuzumab (anti-SLAMF7) has been cited by 1 Publication

Purity & Quality Control

Batch: Purity: 99% Protein concentration: 10.96 mg/ml Endotoxin Level: ＜1EU/mg

99

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Biological Activity

Description	Elotuzumab (anti-SLAMF7, BMS-901608, PDL063, HuLuc63) is a humanized monoclonal antibody that binds human signaling lymphocytic activation molecule F7 (hSLAMF7, also known as CS1, CD319, or CRACC). Elotuzumab shows a dual mechanism of action that includes the direct activation of natural killer (NK) cells and the induction of NK cell–mediated antibody-dependent cellular cytotoxicity.

References

[1] Natalie A Bezman, et al. Blood Adv . 2017 May 8;1(12):753-765.

Product Details

CAS No.	915296-00-3
Molecular Weight	145 kD
Isotype	Human IgG1, κ
Source	CHO cells
Sterility	0.2 μM filtered
Formulation	PBS Buffer, PH 7.4
Storage (From the date of receipt)	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.

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Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID