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Gadodiamide

Synonyms: Omniscan, GDD

Gadodiamide (GDD, Omniscan) is a widely used magnetic resonance imaging (MRI) contrast agent with a high renal toxicity.

Gadodiamide Chemical Structure

Gadodiamide Chemical Structure

CAS: 131410-48-5

Selleck's Gadodiamide has been cited by 1 publication

Purity & Quality Control

Batch: S500001 Water] 100 mg/mL] false] DMSO] Insoluble] false] Ethanol] Insoluble] false Purity: 99.90%
99.90

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Biological Activity

Description Gadodiamide (GDD, Omniscan) is a widely used magnetic resonance imaging (MRI) contrast agent with a high renal toxicity.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04511767 Completed Autism Spectrum Disorder|Global Developmental Delay|Language Disorder Children''s Hospital of Fudan University September 1 2019 --
NCT00908310 Completed Chronic Kidney Disease|Renal Insufficiency GE Healthcare|i3 Statprobe May 2009 Phase 4
NCT00364585 Completed Benign Prostatic Hyperplasia Weill Medical College of Cornell University May 2006 Phase 4

Chemical lnformation & Solubility

Molecular Weight 573.66 Formula

C16H26GdN5O8
CAS No. 131410-48-5 SDF --
Smiles [Gd+3].CNC(=O)CN(CCN(CCN(CC([O-])=O)CC(=O)NC)CC([O-])=O)CC([O-])=O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

Water : 100 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble


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In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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