Home Biosimilar Antibodies Transmembrane Transporters Others Glembatumumab vedotin For research use only.
Not for use in humans.

Glembatumumab vedotin

Synonyms: CDX-011 (DOX), CR011,CR011-vcMMAE

Glembatumumab vedotin (CDX-011 (DOX), CR011,CR011-vcMMAE) is an antibody-drug conjugate (ADC) composed of an fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB), conjugated to Monomethyl Auristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Glembatumumab vedotin has the potential for use in research of Breast cancer (TNBC) and advanced or metastatic melanoma.

Glembatumumab vedotin

CAS No. 1182215-65-1

Click to purchase the isotype control of Glembatumumab vedotin

Purity & Quality Control

Batch: Purity: 99% Protein concentration: Endotoxin Level: ＜1EU/mg
99

Biological Activity

Description Glembatumumab vedotin (CDX-011 (DOX), CR011,CR011-vcMMAE) is an antibody-drug conjugate (ADC) composed of an fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB), conjugated to Monomethyl Auristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Glembatumumab vedotin has the potential for use in research of Breast cancer (TNBC) and advanced or metastatic melanoma.

Product Details

CAS No. 1182215-65-1
ADC antiody Glembatumumab
ADC cytotoxin MMAE
Formulation 1xPBS
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

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