Glucosamine

Synonyms: 2-amino-2-deoxy-D-glucose

Glucosamine (2-amino-2-deoxy-D-glucose) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is commonly used as a treatment for osteoarthritis. Glucosamine(GS) treatment selectively downregulates HIF-1α at the protein level in YD-8 cells via interference of production of the citric acid cycle metabolites.

Glucosamine Chemical Structure

Glucosamine Chemical Structure

CAS: 3416-24-8

Selleck's Glucosamine has been cited by 1 publication

Purity & Quality Control

Batch: Purity: >97%
97

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Biological Activity

Description Glucosamine (2-amino-2-deoxy-D-glucose) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is commonly used as a treatment for osteoarthritis. Glucosamine(GS) treatment selectively downregulates HIF-1α at the protein level in YD-8 cells via interference of production of the citric acid cycle metabolites.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05305937 Not yet recruiting Malignant Tumor of Breast|Benign Breast Lumps|High-Risk Breast Cancer Meir Medical Center|Tel Aviv University May 2022 Not Applicable
NCT05038436 Completed Cholesterol Lowering Certmedica International GmbH|University Hospital Bonn September 16 2021 Not Applicable
NCT03827161 Completed Healthy Subject|Overweight Fred Hutchinson Cancer Center August 1 2017 Phase 1
NCT03743896 Completed Osteoarthritis Knee Lynk Biotechnologies Pte Ltd|T&T Family Health Clinic and Surgery Singapore|Temasek Polytechnic School of Applied Science Singapore May 18 2016 Phase 4
NCT02882438 Unknown status Foot Infection Tinea Pedis Ahmed A. H. Abdellatif|Al-Azhar University January 2016 Phase 1

Chemical lnformation & Solubility

Molecular Weight 179.17 Formula

C6H13NO5

CAS No. 3416-24-8 SDF --
Smiles NC(C=O)C(O)C(O)C(O)CO
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 36 mg/mL ( (200.92 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 36 mg/mL

Ethanol : Insoluble


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In vivo
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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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