Iodixanol

Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography.

Iodixanol Chemical Structure

Iodixanol Chemical Structure

CAS: 92339-11-2

Purity & Quality Control

Batch: Purity: 99.96%
99.96

Biological Activity

Description Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01580046 Unknown status Kidney Failure Chronic Yong Huo|Peking University First Hospital April 2012 Phase 4
NCT01475097 Completed Drug Safety GE Healthcare|i3 Statprobe October 2011 Phase 4
NCT01376089 Completed Patient Comfort and Safety GE Healthcare|i3 Statprobe May 2011 Phase 4
NCT00209417 Terminated Renal Insufficiency|Diabetes Mellitus GE Healthcare|ABX CRO|Examination Management Services Inc.|Covance|Quintiles Inc.|Averion International Corporation June 2005 Phase 4

Chemical lnformation & Solubility

Molecular Weight 1550.18 Formula

C35H44I6N6O15

CAS No. 92339-11-2 SDF --
Smiles CC(=O)N(CC(O)CN(C(C)=O)C1=C(I)C(=C(I)C(=C1I)C(=O)NCC(O)CO)C(=O)NCC(O)CO)C2=C(I)C(=C(I)C(=C2I)C(=O)NCC(O)CO)C(=O)NCC(O)CO
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 100 mg/mL ( (64.5 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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