Iohexol

Synonyms: Omnipaque

Iohexol (Omnipaque) is a radiographic contrast agent that can be used as an exogenous filtration marker for accurate glomerular filtration rate (GFR) estimates.

Iohexol Chemical Structure

Iohexol Chemical Structure

CAS: 66108-95-0

Purity & Quality Control

Batch: S453101 DMSO] 100 mg/mL] false] Water] 100 mg/mL] false] Ethanol] 100 mg/mL] false Purity: 99.81%
99.81

Biological Activity

Description Iohexol (Omnipaque) is a radiographic contrast agent that can be used as an exogenous filtration marker for accurate glomerular filtration rate (GFR) estimates.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05136963 Not yet recruiting Kidney Function Test Centre Hospitalier Universitaire de Saint Etienne June 2024 Phase 1
NCT05536804 Recruiting Overweight|Obesity|Chronic Kidney Disease|Type 2 Diabetes|T2D Eli Lilly and Company February 8 2023 Phase 2
NCT04993872 Active not recruiting HIV-infected Patient Kidney Transplant Recipient Institut de Médecine et d''Epidémiologie Appliquée - Fondation Internationale Léon M''Ba|LAMBERT ASSOUMOU/ UNITE 1136 INSERM|Sebastien GALLIEN/Henri Mondor University Hospital- Infectiology Department|THOMAS STEHL/ HENRI MONDOR HOSPITAL-Department of Nephrology September 29 2022 Phase 4
NCT05460169 Recruiting Uncontrolled Hypertension|Autosomal Dominant Polycystic Kidney Disease|Renal Denervation University of Erlangen-Nürnberg Medical School June 14 2022 Not Applicable
NCT05307172 Not yet recruiting Chronic Kidney Diseases|Diabetes|Obesity Institut National de la Santé Et de la Recherche Médicale France|Centre Hospitalier Universitaire Amiens|Biobanque de Picardie May 3 2022 --

Chemical lnformation & Solubility

Molecular Weight 821.14 Formula

C19H26I3N3O9

CAS No. 66108-95-0 SDF --
Smiles CC(=O)N(CC(O)CO)C1=C(I)C(=C(I)C(=C1I)C(=O)NCC(O)CO)C(=O)NCC(O)CO
Storage (From the date of receipt) 3 years-21°C powder

In vitro
Batch:

DMSO : 100 mg/mL ( (121.78 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 100 mg/mL

Ethanol : 100 mg/mL


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In vivo
Batch:

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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