Menadione bisulfite sodium

Synonyms: Menadione sodium bisulfite, Vitamin K3 sodium bisulfite

Menadione(Vitamin K3) bisulfite sodium, a fat-soluble compound, is an inhibitor of Cdc25 phosphatase and mitochondrial DNA polymerase γ (pol γ), used as a nutritional supplement.

Menadione bisulfite sodium Chemical Structure

Menadione bisulfite sodium Chemical Structure

CAS: 130-37-0

Selleck's Menadione bisulfite sodium has been cited by 1 publication

Purity & Quality Control

Batch: S595301 DMSO] 55 mg/mL] false] Water] 55 mg/mL] false] Ethanol] Insoluble] false Purity: 99.92%
99.92

Choose Selective phosphatase Inhibitors

Biological Activity

Description Menadione(Vitamin K3) bisulfite sodium, a fat-soluble compound, is an inhibitor of Cdc25 phosphatase and mitochondrial DNA polymerase γ (pol γ), used as a nutritional supplement.
Targets
Cdc25 phosphatase [1] pol γ [2]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01094444 Completed Folliculitis Per Pfeiffer|Odense University Hospital May 2010 Phase 2
NCT00656786 Completed EGFR Inhibitor-associated Rash Spectrum Pharmaceuticals Inc April 3 2008 Phase 1

Chemical lnformation & Solubility

Molecular Weight 276.24 Formula

C11H9NaO5S

CAS No. 130-37-0 SDF --
Smiles [Na+].CC1(CC(=O)C2=CC=CC=C2C1=O)[S]([O-])(=O)=O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 55 mg/mL ( (199.1 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 55 mg/mL

Ethanol : Insoluble


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In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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