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Ociperlimab (Anti-TIGIT)

Synonyms: BGB-A1217

Catalog No.A2970 Purity: 99%

Ociperlimab (anti-TIGIT) is a humanized immunoglobulin G1 (IgG1) monoclonal antibody targeting the co-inhibitory molecule and immune checkpoint inhibitor T-cell immunoreceptor with immunoglobulin (Ig) and immunoreceptor tyrosine-based inhibitory motif (ITIM) domains (TIGIT), with potential immune checkpoint inhibitory activity. MW: 145.12 kD.

Ociperlimab (Anti-TIGIT)

Purity & Quality Control

Batch: A297001 Purity: 99% Protein concentration: 11.61mg/ml Endotoxin Level: ＜1EU/mg

99

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Biological Activity

Description	Ociperlimab (anti-TIGIT) is a humanized immunoglobulin G1 (IgG1) monoclonal antibody targeting the co-inhibitory molecule and immune checkpoint inhibitor T-cell immunoreceptor with immunoglobulin (Ig) and immunoreceptor tyrosine-based inhibitory motif (ITIM) domains (TIGIT), with potential immune checkpoint inhibitory activity. MW: 145.12 kD.

References

[1] Chen X, et al. Front Immunol. 2022 Feb 22;13:828319.

Product Details

CAS No.	2342597-93-5
Molecular Weight	145.12
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100mMPro-Ac,20mMArg-Ac，pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

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Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID