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Omalizumab (anti-IgE)

Synonyms: Olizumab, rhuMab-E25

Catalog No.A2044 Purity: 99%

Omalizumab is a recombinant, humanized, monoclonal antibody against human immunoglobulin E (IgE) with a K_D of 0.393 nM. Omalizumab binds to the human FcγRIIb receptors with a K_D of 6.37 uM. Omalizumab has the potential for persistent allergic asthma research.

Omalizumab (anti-IgE)

Click to purchase the isotype control of Omalizumab (anti-IgE)

Purity & Quality Control

Batch: Purity: 99% Protein concentration: 10.44 mg/ml Endotoxin Level: ＜1 EU/mg

99

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Biological Activity

Description	Omalizumab is a recombinant, humanized, monoclonal antibody against human immunoglobulin E (IgE) with a K_D of 0.393 nM. Omalizumab binds to the human FcγRIIb receptors with a K_D of 6.37 uM. Omalizumab has the potential for persistent allergic asthma research.

In Vivo
In vivo	Omalizumab (anti-IgE) is effective in controlling the allergic symptoms of allergic rhinitis by lowering inflammatory mediator CysLT levels of nasal lavage in an experimental allergic rhinitis model.^[1]
Animal Research	Animal models: Sprague Dawley rats Dosages: 0.5mg Administration: s.c. [1]

References

[1] Bozkurt MK, et al. Turk J Med Sci. 2014;44(3):439-47.

Product Details

CAS No.	242138-07-4
Isotype	Human IgG1
Application	Omalizumab (anti-IgE)
Sterility	0.2 μM filtered
Formulation	PBS Buffer, PH 7.4
Storage (From the date of receipt)	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.

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Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID