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Orbifloxacin

Name: Orbifloxacin
Brand: Selleck Chemicals
SKU: S4150

Synonyms: CP-104354

Catalog No.S4150 Purity: 99.82%

Orbifloxacin(CP-104354) is a synthetic broad-spectrum fluoroquinolone antibiotic.

Orbifloxacin Chemical Structure

CAS: 113617-63-3

Purity & Quality Control

Batch: S415001 0.5MNAOH] 3 mg/mL] false] DMSO] 0.05 mg/mL] false] Water] Insoluble] false Purity: 99.82%

99.82

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Choose Selective Antibiotics Inhibitors

Biological Activity

Description	Orbifloxacin(CP-104354) is a synthetic broad-spectrum fluoroquinolone antibiotic.

In vitro
In vitro	Orbifloxacin is a third generation of fluoroquinolone that exhibits increased antibacterial activity against the Enterobacteriaceae, gram-negative and gram-positive bacteria, anaerobes, and mycobacteria. The minimum inhibitory concentrations (MICs) of Orbifloxacin against 240 field S. intermedius isolates (69 skin and 171 ear isolates) ranges from 0.016 to 8 mg/L, with MIC50 and MIC90 equal to 0.5 and 1 mg/L, respectively. ^[1]

References

[1] Ganière JP, et al. Res Vet Sci, 2004, 77(1), 67-71

Chemical lnformation & Solubility

Molecular Weight	395.38	Formula	C₁₉H₂₀F₃N₃O₃
CAS No.	113617-63-3	SDF	Download Orbifloxacin SDF
Smiles	CC1CN(CC(N1)C)C2=C(C3=C(C(=C2F)F)C(=O)C(=CN3C4CC4)C(=O)O)F
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

0.5MNAOH : 3 mg/mL

DMSO : 0.05 mg/mL ( (0.12 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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