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Patritumab (Anti-ERBB3 / HER3)

Synonyms: Human Anti-ERBB3 Recombinant Antibody

Catalog No.A2506 Purity: 99%

Patritumab (Anti-ERBB3 / HER3) is a neutralizing monoclonal antibody targeting ERBB3. Patritumab shows a synergy with Cetuximab (HY-P9905), potently inhibits the phosphorylation of EGFR, HER2, HER3, ERK, and AKT. Patritumab also induces cell apoptosis and suppresses the growth of pancreatic, non-small cell lung cancer, and colorectal cancer xenograft tumors. MW: 145.5 KD.

Patritumab (Anti-ERBB3 / HER3)

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Purity & Quality Control

Batch: Purity: 99% Protein concentration: 13.58mg/ml Endotoxin Level: ＜1EU/mg

99

Choose Selective HER2 Inhibitors

Biological Activity

Description	Patritumab (Anti-ERBB3 / HER3) is a neutralizing monoclonal antibody targeting ERBB3. Patritumab shows a synergy with Cetuximab (HY-P9905), potently inhibits the phosphorylation of EGFR, HER2, HER3, ERK, and AKT. Patritumab also induces cell apoptosis and suppresses the growth of pancreatic, non-small cell lung cancer, and colorectal cancer xenograft tumors. MW: 145.5 KD.

Product Details

CAS No.	1262787-83-6
Molecular Weight	145.5 kDa
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100mMPro-Ac,20mMArg-Ac，pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

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Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID