Home Neuronal Signaling GABA Receptor agonist (R)-baclofen For research use only.

(R)-baclofen

Synonyms: STX 209

(R)-baclofen (STX 209) is a derivative of gamma-aminobutyric acid primarily used to treat spasticity.

(R)-baclofen Chemical Structure

(R)-baclofen Chemical Structure

CAS: 69308-37-8

Selleck's (R)-baclofen has been cited by 1 publication

Purity & Quality Control

Batch: S307201 Water] 8 mg/mL] false] DMSO] Insoluble] false] Ethanol] Insoluble] false Purity: 99.72%
99.72

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Biological Activity

Description (R)-baclofen (STX 209) is a derivative of gamma-aminobutyric acid primarily used to treat spasticity.
Targets
GABAB receptor [1]
In vitro
In vitro Baclofen is a skeletal muscle relaxant used in the treatment of spasticity of spinal and cerebral origin. Although it is marketed as a racemic mixture, only the baclofen R-enantiomer is stereospecifically active at so called GAGAB-receptors. [1] Researchers believe that the enantiomers of baclofen have different properties. It is claimed that the R-(−)-enantiomer is about 100 times more active than the S-(+)-enantiomer.

Chemical lnformation & Solubility

Molecular Weight 213.66 Formula

C10H12ClNO2
CAS No. 69308-37-8 SDF Download (R)-baclofen SDF
Smiles C1=CC(=CC=C1C(CC(=O)O)CN)Cl
Storage (From the date of receipt)

In vitro
Batch:

Water : 8 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble


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In vivo
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