Home Transmembrane Transporters Calcium Channel inhibitor Tetracaine HCl For research use only.

Tetracaine HCl

Synonyms: Amethocaine hydrochloride

Tetracaine HCl (Amethocaine hydrochloride) is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor.

Tetracaine HCl Chemical Structure

Tetracaine HCl Chemical Structure

CAS: 136-47-0

Selleck's Tetracaine HCl has been cited by 1 publication

Purity & Quality Control

Batch: Purity: 100%
100

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Biological Activity

Description Tetracaine HCl (Amethocaine hydrochloride) is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor.
Targets
Calcium channel [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04794842 Active not recruiting Intratympanic Steroid Injection|Idiopathic Sudden Sensorineural Hearing Loss|Meniere Disease Our Lady of the Lake Hospital|Louisiana State University Health Sciences Center - New Orleans August 1 2021 Early Phase 1
NCT01952990 Completed Anesthesia St. Renatus LLC|Triligent International|Analytical Bio-Chemistry Laboratories Inc.|Rho Inc. September 2013 Phase 2
NCT01304316 Completed Anesthesia St. Renatus LLC|Ground Zero Pharmaceuticals|Rho Inc. September 2010 Phase 2
NCT00747669 Suspended Pain ZARS Pharma Inc. September 2008 Phase 4

Chemical lnformation & Solubility

Molecular Weight 300.82 Formula

C15H24N2O2.HCl
CAS No. 136-47-0 SDF Download Tetracaine HCl SDF
Smiles CCCCNC1=CC=C(C=C1)C(=O)OCCN(C)C.Cl
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 60 mg/mL ( (199.45 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 60 mg/mL

Ethanol : 30 mg/mL


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In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO % % Tween 80 % ddH2O
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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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