Tisotumab vedotin

Synonyms: TF-011-MMAE, HuMax-TF-ADC

Tisotumab vedotin (TF-011-MMAE, HuMax-TF-ADC) is an antibody-drug conjugate (ADC) composed of a fully human monoclonal antibody to tissue factor III (thromboplastin) also known as CD142, conjugated to Monomethyl Auristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinylp-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Tisotumab vedotin has the potential for use in research of solid tumors mainly in cervical cancer.

Tisotumab vedotin

CAS No. 1418731-10-8

Click to purchase the isotype control of Tisotumab vedotin

Purity & Quality Control

Batch: D405101 Purity: 98% Protein concentration: 9.88mg/ml Endotoxin Level: <1EU/mg
98

Choose Selective CD markers Inhibitors

Biological Activity

Description Tisotumab vedotin (TF-011-MMAE, HuMax-TF-ADC) is an antibody-drug conjugate (ADC) composed of a fully human monoclonal antibody to tissue factor III (thromboplastin) also known as CD142, conjugated to Monomethyl Auristatin E (MMAE), via a cleavable maleimidocaproyl-valyl-citrullinylp-aminobenzyloxycarbonyl (mc-val-cit-PABC) type linker. Tisotumab vedotin has the potential for use in research of solid tumors mainly in cervical cancer.

Product Details

CAS No. 1418731-10-8
DAR 4.2
ADC antiody Tisotumab
ADC cytotoxin MMAE
Formulation 1xPBS
Storage
(From the date of receipt)
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

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