Trastuzumab-deruxtecan (DS-8201a, T-DXd)

Synonyms: DS-8201

Trastuzumab deruxtecan (DS-8201a, T-DXd) is an antibody-drug conjugate (ADC) composed of an anti-HER2 (human epidermal growth factor receptor 2) antibody and a cytotoxic topoisomerase I inhibitor. Trastuzumab deruxtecan shows durable antitumor activity. Trastuzumab deruxtecan has a molecular weight of 153KDa. This product is supplied as 10mg/ml PBS solution.This product is discontinued. We recommend the replacement products: D4001.

Trastuzumab-deruxtecan (DS-8201a, T-DXd) Chemical Structure

Trastuzumab-deruxtecan (DS-8201a, T-DXd) Chemical Structure

CAS: 1826843-81-5 (ADC)

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Purity & Quality Control

Batch: E020001 Purity: 99.86%
99.86

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Biological Activity

Description Trastuzumab deruxtecan (DS-8201a, T-DXd) is an antibody-drug conjugate (ADC) composed of an anti-HER2 (human epidermal growth factor receptor 2) antibody and a cytotoxic topoisomerase I inhibitor. Trastuzumab deruxtecan shows durable antitumor activity. Trastuzumab deruxtecan has a molecular weight of 153KDa. This product is supplied as 10mg/ml PBS solution.This product is discontinued. We recommend the replacement products: D4001.

Chemical lnformation & Solubility

Molecular Weight 153000 Formulation 10mg/mL in PBS
DAR 7.8 Antibody Trastuzumab
ADC Cytotoxin DXd Formula N/A
CAS No. 1826843-81-5 (ADC) Storage (From the date of receipt) 1 year -80°C in solvent
Shipping Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Frequently Asked Questions

Question 1:
What’s the solvent of this ADC drug? And what’s its concentration?

Answer:
The solvent is a PBS solution. The concentration is 10mg/ml.

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