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Travoprost

Name: Travoprost
Brand: Selleck Chemicals
SKU: S3738

Synonyms: Travoprostum

Catalog No.S3738 Purity: 99.88%

Travoprost (Travoprostum) is a PGF2a analog that was launched as an ophthalmic solution administered topically for the treatment of elevated intraocular hypertension as a result of open-angle glaucoma, a common optic neuropathy, and a leading cause of blindness. It can act as an agonist of prostaglandin F receptor.

Travoprost Chemical Structure

CAS: 157283-68-6

Purity & Quality Control

Batch: Purity: 99.88%

99.88

Related compound libraries

Choose Selective Prostaglandin Receptor Inhibitors

Biological Activity

Description

Targets

prostaglandin F receptor ^[1]
(HEK-293 cells)

42.3 nM(EC50)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-01-11)
NCT00705757	Completed	Glaucoma\|Application Site Pigmentation Changes	Summa Health System	March 2008	Phase 4

References

[1] Sharif NA, et al. J Ocul Pharmacol Ther. 2002, 18(4):313-24.

Chemical lnformation & Solubility

Molecular Weight	500.55	Formula	C₂₆H₃₅F₃O₆
CAS No.	157283-68-6	SDF	Download Travoprost SDF
Density	1.245 g/mL
Smiles	CC(C)OC(=O)CCCC=CCC1C(CC(C1C=CC(COC2=CC=CC(=C2)C(F)(F)F)O)O)O
Storage (From the date of receipt)	2 years -80°C liquid	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	2 years -80°C liquid		1 month-20°Cin solvent

In vitro
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In vivo
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In vivo Formulation Calculator

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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