Home DNA Damage/DNA Repair DNA/RNA Synthesis chemical 2’-deoxyuridine For research use only.

2’-deoxyuridine

Synonyms: dU, 2'-dU

2'-deoxyuridine (dU, 2'-dU) is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms.

2’-deoxyuridine Chemical Structure

2’-deoxyuridine Chemical Structure

CAS: 951-78-0

Purity & Quality Control

Batch: S550501 DMSO] 45 mg/mL] false] ] ] false] ] ] false Purity: 99.98%
99.98

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Biological Activity

Description 2'-deoxyuridine (dU, 2'-dU) is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03866954 Withdrawn Mitochondrial Diseases|Metabolic Disease|Inborn Errors of Metabolism St George''s University of London|Neovii Biotech November 2024 Phase 2
NCT05703763 Not yet recruiting Giant Cell Arteritis Hopital du Sacre-Coeur de Montreal March 2024 --
NCT06185491 Not yet recruiting Diabetes Mellitus Nantes University Hospital March 2024 Not Applicable
NCT06078384 Not yet recruiting Triple-negative Breast Cancer UNICANCER|MSD France|Vall d''Hebron Institute of Oncology|SOLTI Breast Cancer Research Group February 1 2024 Phase 2

Chemical lnformation & Solubility

Molecular Weight 228.20 Formula

C9H12N2O5
CAS No. 951-78-0 SDF --
Smiles C1C(C(OC1N2C=CC(=O)NC2=O)CO)O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 45 mg/mL ( (197.19 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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