Home Microbiology Parasite inhibitor - DNA/RNA Synthesis inhibitor Amodiaquine For research use only.

Amodiaquine

Amodiaquine is a synthetic aminoquinoline that acts by binding to the protozoal or parasitic DNA and preventing DNA and RNA production and subsequent protein synthesis. It is used for the therapy of malaria.

Amodiaquine Chemical Structure

Amodiaquine Chemical Structure

CAS: 86-42-0

Selleck's Amodiaquine has been cited by 5 publications

Purity & Quality Control

Batch: S594801 DMSO] 71 mg/mL] false] Ethanol] 22 mg/mL] false] Water] Insoluble] false Purity: 99.50%
99.50

Related compound libraries

Choose Selective Parasite Inhibitors

Biological Activity

Description Amodiaquine is a synthetic aminoquinoline that acts by binding to the protozoal or parasitic DNA and preventing DNA and RNA production and subsequent protein synthesis. It is used for the therapy of malaria.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05979896 Recruiting Malaria Malaria Consortium July 28 2023 Phase 4
NCT05478954 Active not recruiting Malaria Malaria Consortium July 15 2022 Phase 4
NCT05471544 Active not recruiting Malaria Malaria Consortium July 18 2022 Phase 3
NCT05343312 Active not recruiting Malaria Centro de Investigacao em Saude de Manhica|United States Agency for International Development (USAID) March 16 2022 Phase 4
NCT04002687 Completed Malaria Medicines for Malaria Venture|Richmond Pharmacology Limited April 4 2019 Phase 1

Chemical lnformation & Solubility

Molecular Weight 355.86 Formula

C20H22ClN3O
CAS No. 86-42-0 SDF --
Smiles CCN(CC)CC1=C(C=CC(=C1)NC2=C3C=CC(=CC3=NC=C2)Cl)O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 71 mg/mL ( (199.51 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 22 mg/mL

Water : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

Please enter your name.
Please enter your email. Please enter a valid email address.
Please write something to us.
Tags: buy Amodiaquine | Amodiaquine supplier | purchase Amodiaquine | Amodiaquine cost | Amodiaquine manufacturer | order Amodiaquine | Amodiaquine distributor