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Clevidipine Butyrate

Name: Clevidipine Butyrate
Brand: Selleck Chemicals
SKU: S2080
Rating: 5 (1 reviews)

Synonyms: Cleviprex

Catalog No.S2080 Purity: 99.79%

Clevidipine Butyrate(Cleviprex) is a dihydropyridine calcium channel blocker, uses as an agent for the reduction of blood pressure.

Clevidipine Butyrate Chemical Structure

CAS: 167221-71-8

Selleck's Clevidipine Butyrate has been cited by 1 publication

Purity & Quality Control

Batch: S208001 DMSO] 91 mg/mL] false] Ethanol] 3 mg/mL] false] Water] Insoluble] false Purity: 99.79%

99.79

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Biological Activity

Description

Clevidipine Butyrate(Cleviprex) is a dihydropyridine calcium channel blocker, uses as an agent for the reduction of blood pressure.

Targets

Calcium channel ^[1]

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-01-11)
NCT01042574	Withdrawn	Hypertension\|Intracranial Hemorrhage\|Subarachnoid Hemorrhage	Methodist Healthcare\|The Medicines Company	May 2010	Phase 4

Chemical lnformation & Solubility

Molecular Weight	456.32	Formula	C₂₁H₂₃Cl₂NO₆
CAS No.	167221-71-8	SDF	Download Clevidipine Butyrate SDF
Smiles	CCCC(=O)OCOC(=O)C1=C(NC(=C(C1C2=C(C(=CC=C2)Cl)Cl)C(=O)OC)C)C
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 91 mg/mL ( (199.42 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 3 mg/mL

Water : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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