Home Microbiology Parasite inhibitor Cyromazine For research use only.

Cyromazine

Synonyms: Cyromazin,CGA-72662

Cyromazine(Cyromazin,CGA-72662) is a triazine insect growth regulator used as an insecticide and an acaricide.

Cyromazine Chemical Structure

Cyromazine Chemical Structure

CAS: 66215-27-8

Purity & Quality Control

Batch: S416701 DMSO] 33 mg/mL] false] Ethanol] 2 mg/mL] false] Water] 1 mg/mL] false Purity: 99.2%
99.2

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Biological Activity

Description Cyromazine(Cyromazin,CGA-72662) is a triazine insect growth regulator used as an insecticide and an acaricide.
In vitro
In vitro

Cyromazine, a cyclopropyl derivative of melamine, is an insect growth regulator, affects larval and pupal cuticles in dipterans and some other insects. The mode of action of cyromazine may be to inhibit the synthesis of chitin and cuticular proteins. Cyromazine may, however, act on some step(s) of sclerotization of the cuticle. Cyromazine does not significantly affect PAH and DHFR activity. Cyromazine changes the relative content of phenylalanine and tyrosine, or the total amount and profile of amino acids of puparial cuticles, which showed a larviform shape typical for cyromazine intoxication. [1]
In Vivo
In vivo

Cyromazine can be hydrolysed at extreme pH or photodegraded leading to the stable heterocyclic structure melamine (1,3,5-triazine-2,4,6-triamine). It can also be metabolized via dealkylation reactions in both plants and animals and undergoes environmental degradation to form melamin. [2]

Chemical lnformation & Solubility

Molecular Weight 166.18 Formula

C6H10N6
CAS No. 66215-27-8 SDF Download Cyromazine SDF
Smiles C1CC1NC2=NC(=NC(=N2)N)N
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 33 mg/mL ( (198.57 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 2 mg/mL

Water : 1 mg/mL


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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