Cytarabine hydrochloride

Cytarabine is a pyrimidine nucleoside analog that is used mainly in the treatment of leukemia. It is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA.

Cytarabine hydrochloride Chemical Structure

Cytarabine hydrochloride Chemical Structure

CAS: 69-74-9

Selleck's Cytarabine hydrochloride has been cited by 21 publications

Purity & Quality Control

Batch: S558201 DMSO] 55 mg/mL] false] ] ] false] ] ] false Purity: 98%
98

Choose Selective DNA/RNA Synthesis Inhibitors

Biological Activity

Description Cytarabine is a pyrimidine nucleoside analog that is used mainly in the treatment of leukemia. It is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05697510 Recruiting Acute Myeloid Leukemia (AML) Nantes University Hospital March 16 2023 Phase 1
NCT05319587 Recruiting Leukemia Myeloid Acute Moleculin Biotech Inc. September 29 2022 Phase 1|Phase 2

Chemical lnformation & Solubility

Molecular Weight 279.68 Formula

C9H13N3O5.HCl

CAS No. 69-74-9 SDF --
Smiles C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O.Cl
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 55 mg/mL ( (196.65 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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