Home Immunology & Inflammation COX inhibitor Naproxen For research use only.

Naproxen

Naproxen is an anti-inflammatory agent with analgesic and antipyretic properties. It is a nonselective inhibitor of COX-1 and COX-2.

Naproxen Chemical Structure

Naproxen Chemical Structure

CAS: 22204-53-1

Selleck's Naproxen has been cited by 2 publications

Purity & Quality Control

Batch: S517701 DMSO] 46 mg/mL] false] ] ] false] ] ] false Purity: 99.99%
99.99

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Biological Activity

Description Naproxen is an anti-inflammatory agent with analgesic and antipyretic properties. It is a nonselective inhibitor of COX-1 and COX-2.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05900336 Not yet recruiting Dysmenorrhea|Menstrual Pain|Non-steroidal Anti-inflammatory Drug Mclean Hospital|United States Department of Defense|NorthShore University HealthSystem January 1 2024 Phase 4
NCT05844995 Recruiting Orthodontic Pain Johnson & Johnson Consumer Inc. (J&JCI)|Johnson & Johnson Consumer and Personal Products Worldwide September 13 2023 Phase 1
NCT05411718 Recruiting T Cells|Colorectal Cancer|Lynch Syndrome M.D. Anderson Cancer Center|National Institutes of Health (NIH)|National Cancer Institute (NCI) March 21 2023 Phase 2
NCT05026320 Completed Soft Tissue Injury Bayer|Deutsche Sporthochschule Köln August 8 2021 Phase 2

Chemical lnformation & Solubility

Molecular Weight 230.26 Formula

C14H14O3
CAS No. 22204-53-1 SDF --
Smiles CC(C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 46 mg/mL ( (199.77 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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